Sanofi Group Precision Immunology Principal Data Scientist in Cambridge, Massachusetts

Precision Immunology Principal Data Scientist

The Immunology and Inflammation Research and Early Development Therapeutic Area in Sanofi is building a world-class immunology team and is seeking a highly motivated computational scientist to lead in silico analytical projects for patients stratification and novel target identification in the fields of Type 2 Immunity and Fibrosis, Immune Checkpoint Biology, Type 1 Diabetes, Autoimmunity and Innate Immunity.

We are seeking a Principal Data Scientist in the Precision Immunology Cluster of our Immunology & Inflammation Research Therapeutic Area . The successful candidate will have extensive experience in the development and application of machine learning, statistical and computational methods to solve biological problems, excellent oral and written communication skills, and the ability to learn and acquire new techniques and methodologies. The candidate is expected to lead and execute analytical projects and develop analytical strategies for the identification of novel therapeutic targets and the discovery of predictive biomarkers to aid patients stratification and clinical development plans.

This exciting role will afford scientists the opportunity to be intimately involved in early discovery research and pre-clinical development.

Summary of Key Responsibilities:

  • Lead projects to Identify candidate therapeutic targets and biomarkers for immunology, through integrated analysis of high-throughput molecular data and clinical phenotypes

  • Collaborate with wet-lab and computational scientific teams and champion projects from discovery to early clinical development.

  • Develop innovative and creative computational approaches to understand complex immune conditions using multi-dimensional –omics and clinical data

  • Establish interactions with collaborators within and outside the Immunology and Inflammation Research and Early Development Therapeutic Area.

  • Prepare publications, research and clinical/regulatory documentation in accordance with Sanofi quality standards.

Essential Qualifications:

  • PhD in computational biology, computer science, statistics, or a related quantitative science field with 6+ years of project-based work in computational application in biology related fields or MS in computational biology, computer science, statistics, or a related quantitative science field with 8+ years of project-based work in computational application in biology related fields

  • Proficiency in analysing data with R, Matlab or Python

  • Working knowledge of Linux/HPC and shell scripting

Preferred Qualifications:

  • Strong interested in biology and immunological diseases, liaise with scientists from Immunology and Inflammation to help define and address biological questions with computational and analytical approaches

  • Proficiency in biostatistics, linear/non-linear regression models, dimensionality reduction, clustering, machine learning approaches including SVMs, and Random Forest

  • Ability to develop, benchmark and apply predictive algorithms to identify novel biomarkers, dissect relationships and generate hypotheses

  • Experience with Bayesian analysis and causal inference

  • Excellent written and oral communication skills

  • Excellent interpersonal and team skills

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life