Sanofi Group Technologist -Downstream BRD in Toronto, Ontario

TECHNOLOGIST

(4 MONTH TEMPORARY EMPLOYMENT OPPORTUNITY)

Reference: R2457601

Location: Sanofi Pasteur Limited / North York, Ontario

Address: 1755 Steeles Ave W, North York, ON M2R 3T4

Department: Downstream Purification Platform

Reporting To: Scientist

Required Education: Bachelor of Science (Biochemistry, Chemistry) or equivalent

Sanofi Pasteur, the vaccines division of Sanofi, is the largest company in the world devoted entirely to human vaccines. For over 100 years, we’ve provided life-saving vaccines for the prevention and treatment of infectious diseases.

Sanofi Pasteur Limited, located in Toronto, is one of the company's four major R&D and manufacturing sites. We are home to Sanofi Pasteur's North American centre for Analytical and Bioprocess R&D. As well, we are the largest Canadian vaccine producer: each year, we manufacture 50 million doses of vaccine and distribute them to more than 90 countries around the world, helping to protect against 20 infectious diseases. This variety of activities offers employees diverse opportunities for personal and professional growth. Our company attracts some of the best minds in the business from across the globe. Our 1,300 employees give us their best and we offer the best in return.

Sanofi Pasteur Limited is looking for motivated and results driven individuals to join our Downstream Purification Platform Department as a Technologist. Key responsibilities will include the following:

Position Summary:

  1. Develop and implement purification experiments and protocols for viral and bacterial antigens under GXP
  • Using high throughput technology to develop and execute experiments to purify viral and bacterial antigens for process development and improvement.

  • Perform process scale up and process definition studies

  • Experiments require knowledge of protein purification, virus purification, and vaccine candidate characterization, wet chemistry and computerized instrumentation (HPLC, FPLC, UV, TFF, etc.)

  • Collaborate with members of BRD, ARD and QC in order to co-ordinate experiments, testing, and troubleshooting.

  • Organize and schedule experiments in order to ensure that work is timely and efficiently performed.

  • Maintain accurate records of all experimental data.

  • Preparing Certificates of Analyses.

  1. Develop analytical techniques for in-process monitoring and process control.
  • Develop in-process tests to ensure product quality and reproducibility.

  • Improvement of existing protocols for protein purification and for analysis of purity.

  • Implementation of new analytical instruments.

  • Ensure all logbooks are signed, equipment maintained and monitored.

  1. Perform SDS-PAGE, Western Blots, and Protein assays. Operate and maintain lab and equipment. Preparation of reports, methods, SOPs, BPRs
  • Prepare and run SDS-PAGE and Western blots throughout the purification stages

  • Prepare and run protein assays,

  • Quantify purity and yields by HPLC and colorimetric assays

  • Maintain operating condition of lab equipment.

  • Prepare reports summarizing experimental and assay results to be disseminated to supervisor and external customers.

  • Write new experimental and assay methods as they are developed.

  • Write, edit and review SOPs and BPRs.

  1. Compliance with employment and health & safety legislation and work within the policies, procedures and regulations.
  • Takes every reasonable precaution to ensure the health and safety for self and co-workers.

  • Uses required protective equipment and clothing

  • Reports critical incidents and accidents to the appropriate authorities.

  • Participates in the investigation of incidents and work related illnesses.

  • Responds promptly to all health and safety concerns or incidents and completes the appropriate documentation in a timely manner.

  • Cooperates and assists the Joint Health and Safety Committee that is carrying out its functions.

  • Participates and contributes to the PASS objectives.

Education and Experience:

  • Bachelor of Science Degree (Biochemistry, Chemistry) or equivalent.

  • Minimum of one (1) year of previous relevant experience in a Biotechnology, Pharmaceutical company, or University Research Institution. High throughput process development experience is preferred.

  • Demonstrated ability to work independently and make quick decisions in accordance with SOPs and training.

  • Basic computer skills and the ability to enter data accurately and in a timely manner.

  • Must be proficient in Microsoft Excel

Hours of Work:

Monday to Friday 8:00a.m.-4:00p.m.

Sanofi is an equal opportunity employer committed to diversity and inclusion. Our goal is to a ttract, develop and retain highly talented employees from diverse backgrounds, allowing us to benefit from a wide variety of experiences and perspectives. We welcome and encourage applications from all qualified applicants. Accommodations for persons with disabilities required during the recruitment process are available upon request.

Thank you in advance for your interest.

Only those candidates selected for interviews will be contacted.

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#GD-SP

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

Sanofi, Empowering Life